Kluyveromyces marxianus CCT7735: uma revisão sobre os mecanismos de respostas ao estresse por etanol com aplicação na produção de biocombustível
Palavras-chave:
Etanol, Resíduos agroindustriais, Estresse
Resumo
A produção do etanol como combustível é uma alternativa promissora a utilização dos combustíveis fósseis. Nesse contexto, os resíduos agroindustriais têm despontado como matérias-primas capazes de aumentar a produção de etanol sem competir com a produção de alimentos. Assim, tanto o soro de queijo, quanto subprodutos lignocelulósicos podem ser utilizados como substratos para a produção de etanol. No entanto, a levedura Saccharomyces cerevisiae é incapaz de metabolizar a lactose presente no soro de queijo e de crescer nas elevadas temperaturas requeridas no processo de Sacarificação e Fermentação Simultâneas (SSF) de biomassa lignocelulósica. Por outro lado, Kluyveromyces marxianusCCT7735 é uma linhagem desta levedura, que apresenta potencial para produzir etanol tanto a partir de soro de queijo quanto de subprodutos lignocelulósicos. Isto porque ela fermenta lactose e cresce em altas temperaturas. Todavia, ela tem o seu crescimento inibido em altas concentrações de etanol. Portanto, para viabilizar a produção de etanol, torna-se necessário compreender os mecanismos de resposta ao estresse por etanol em K. marxianus. Sendo assim, este trabalho teve como objetivo descrever e analisar os principais mecanismos de resposta ao estresse por etanol em leveduras,descritos na literatura, através de uma revisão bibliográfica, a fim de compreender como K. marxianus responde ao estresse etanólico. Nesse sentido, a abordagem utilizada nesta pesquisa foi do tipo exploratório, descritivo e bibliográfico.Desta forma, os artigos obtidos a partir das bases de dados eletrônicos foram analisados e sistematizados de acordo com a sua relevância para a compreensão dos mecanismos de respostas ao estresse por etanol em leveduras. A partir da análise dos mecanismos envolvidos na tolerância ao etanol descritos na literatura concluiu-se que eles contribuem para o entendimento das respostas moleculares ao estresse etanólico em K. marxianus. Entretanto, devido à complexidade destes mecanismos torna-se necessário fazer um estudo mais detalhado a nível molecular a fim de compreendê-los melhor.Referências
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DICKEY, A. N.; YIM, W. S.; FALLER, R. Using ergosterol to mitigate the deleterious effects of ethanol on bilayer structure. The Journal of Physical Chemistry B, v.113, p. 2388-2397, 2010.
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DINIZ, R. H. S.; RODRIGUES, M. Q. R. B.; FIETTO, L.G.; PASSOS, F.M.L.; SILVEIRA, W. B. Optimizing and validating the production of ethanol from cheese
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Publicado
2021-05-02
Como Citar
BRITO, A. Kluyveromyces marxianus CCT7735: uma revisão sobre os mecanismos de respostas ao estresse por etanol com aplicação na produção de biocombustível. Revista Científica do UBM, v. 19, n. 37, p. 39-60, 2 maio 2021.
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